I honestly dont know, considering he was almost always under the influence. Weed and alcohol does fuck with ur mind and how u think. I know this from previous experiences, heavy amounts of weed smoke make me act different than the norm. If i was always sober i would probably be a miserable person, that thought out things WAY TOO MUCH. Weed sometimes alters my mood in a matter of minutes after smoking. I can go from sad to glad or the opposite. But one thing that weed does do is intensify what ever it is i am feeling at that time. Plus weed and alcohol have different effects on an individual basis.
Think of what tupac did with a racing, pacing, never sit down, always fuckd up mind state, constantly partying...
Now think if pac would of sat in the studio all day with his mind COMPLETELY clear...
Id love to hear them both.