Yes. Life isn't cookies, fairies, sweet little hobbits.
However, life also isn't black and white, good and evil. People are dynamic, complex, diverse. A murderer is not just a murderer. A pedophile is not just a pedophile. There's more to a person that what their actions show so I feel that it's wrong to disown family for things. If my brother was a pedophile, I wouldn't shield him from the law, but I wouldn't refuse to be a brother to him.
If you have done all you can and your siblings refuse to communicate with you, support you, there's not much you can do, but I have a feeling most people on here who don't communicate with their siblings haven't got to that point of not having any other option.
To not know where your sister lives! Jeremy, you fucking moron!
Now tell me why you don't get along with your family so I can tell you why you're stupid.